rs145954970

This is a regulatory region variant variant.

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GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

urate measurement

Tin A et al. “Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.” Nature Genetics 51(10):1459-1474 (2019)

Allele C

OR 1.66

p —

N 457,690

Large GWAS

multi-ancestry

gout

Nakayama A et al. “Subtype-specific gout susceptibility loci and enrichment of selection pressure on ABCG2 and ALDH2 identified by subtype genome-wide meta-analyses of clinically defined gout patients.” Annals of the Rheumatic Diseases 79(5):657-665 (2020)

Allele C

OR 12.43

p 2.0e-21

N 7,607

Large GWAS

East Asian

smoking status measurement, diet measurement, sex interaction measurement, physical activity, alcohol drinking, uric acid measurement, age at assessment

Namba S et al. “A cross-population compendium of gene-environment interactions.” Nature 651(8106):688-697 (2026)

Allele G

OR —

p 6.0e-10

N 98,320

Large GWAS

multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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