rs3740909

This variant is located in the CDON gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

cell adhesion molecule-related/down-regulated by oncogenes amount

Suhre K et al. “Connecting genetic risk to disease end points through the human blood plasma proteome.” Nature Communications 8:14357 (2017)

Allele T

OR 0.83

p 4.0e-25

N 997

Small GWAS

multi-ancestry

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ClinVar annotation

Benign★★★☆

5 submitters2 publications

not specified; Holoprosencephaly 11; not provided

View on ClinVar →

About CDON

This gene encodes a cell surface receptor that is a member of the immunoglobulin superfamily. The encoded protein contains three fibronectin type III domains and five immunoglobulin-like C2-type domains. This protein is a member of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells and positively regulates myogenesis. [provided by RefSeq, Aug 2011]

View all CDON variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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